Functional Excipients for the Formulation of Solid Oral Dosage Forms
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Starch 1500® used as a binder and disintegrant in high shear wet granulation. Comparison to PVP and Croscarmellose SodiumThis paper illustrates the benefits of utilizing Starch 1500 as both a disintegrant and binder in a high shear wet granulation application in the place of a polymeric binder and super disintegrant.
Starch 1500® Product Information Sheet
Application of Ethylcellulose in Preparation of Extended Release Theophylline Inert Matrix Tablets by Wet GranulationThe outcome of this study illustrates that an aqueous ethylcellulose dispersion (Surelease™) was successfully utilized to formulate and manufacture extended release theophyllin inert matrices. The influence of varying polymer concentration, filler choice and compression force on drug release profiles were studied as well.
Formulation and Process Considerations for Delayed Release Multi-Particulates of Esomeprazole Magnesium This ADS was adapted from the 2008 AAPS poster. The objective of this study was to investigate and establish an application process for an enteric coating system, Acryl-EZE®, aqueous acrylic enteric system, on an esomeprazole magnesium trihydrate (40 mg) multi-particulate system.
The Influence of In Vitro Dissolution Method on Lansoprazole Release from Enteric Coated Mini-TabsADS adapted from 2009 CRS poster, The Influence of In Vitro Dissolution Method on Lansoprazole Release from Enteric Coated Mini-Tabs
Acryl-EZE® 93A Product InformationFeatures and benefits of the Acryl-EZE 93A series of aqueous, acrylic enteric delayed release coating systems.
Acryl-EZE® MP Product InformationFeatures and benefits of the Acryl-EZE MP series of aqueous, acrylic enteric delayed release coating systems.
Evaluation of the Enteric Performance of Lansoprazole Mini-Tabs Coated in a Perforated PanThe focus of this study was to investigate the potential of successful manufacture and enteric coating of lansoprazole mini-tabs using methacrylic acid co-polymers in a perforated pan. Along with other findings, this study will show that the mechanical strength of the mini-tabs significantly improved upon application of a seal-coat.
The Influence of Solvent Type on Extended Release Coating with Ethylcellulose Barrier MembranesThe objective of this work was to investigate the influence of four acceptable solvent combinations on EC solution viscosity and consequent drug release from coated beads.
Evaluation of a Continuous Coating Process for the Application of a Regulatory Compliant Nutritional Enteric Coating on Soft Gelatin CapsulesThe purpose of the study was to evaluate a continuous coating process for the application of a delayed release coating system onto soft gelatin capsules.
New Enteric Coating System (Nutrateric®) for Nutritional SupplementsThis poster reprint summarizes the performance of Nutrateric when applied to tablets or soft gelatin capsules.
The Influence of Pore Former Concentration and Coating Weight Gain on Drug Release from Multi-Particulates Coated with Nutrateric®The outcome of this study successfully illustrates the combination of a pH dependent pore former and an aqueous ethylcellulose dispersion resulted in the desired delayed drug release profiles from multi-particulate systems. Coating level and port former concentrations were tailored to alter the duration of the delay in drug release followed by rapid release in higher pH media.
Opadry® amb - Moisture Vapor TransmissionEvaluation of Opadry amb compared with alternative coating formulations and their effect on moisture uptake.
Development of USP Delayed Release Aspirin Tablets using Opadry® Enteric, Acrylic-Based Coating System The objective of this study was to develop aspirin delayed release tablets that comply with USP requirements.
Drug Release From Acrylic Based Opadry® Enteric (94 Series) Coated TabletsOpadry® Enteric (94 series), enteric coating system, is a fully formulated, delayed release coating system for solid oral dosage forms, based on MAC, specifically the poly [methacrylic acid, methyl methacrylate (1:1), type A].
Opadry® Enteric 91, 94, 95 seriesOpadry Enteric is a family of fully formulated, delayed release coating systems for solid oral dosage forms, which are applied by organic or hydro-alcoholic processing techniques.
Opadry® Enteric Product InformationFeatures and benefits of the Opadry Enteric platform of PVAP (Phthalavin®) based, delayed release coating systems.
Opadry® II - Product Information BrochureImproved efficiency PVA and HPMC coating formulations reduce coating processing time by 25-30% compared with conventional systems. For use in nutritional and pharmacuetical applications.
Opadry® tm - Taste Mask ComparisonProduct technology summary including stability profile, film properties, color effects and regulatory guidelines.
Opadry® fx™ PropertiesProduct technology summary including stability profile, film properties, color effects and regulatory guidelines.
Opaglos® 2 Sales BrochureProduct features and benefits.
Opalux® Tablet Sealant CoatingProduct Overivew.
The Influence of Solvent Type on Extended Release Coating with Ethylcellulose Barrier MembranesThe objective of this work was to investigate the influence of four acceptable solvent combinations on ethylcellulose solution viscosity and consequent drug release from coated beads.
The Influence of Coating System Type on Acetaminophen Release from Ethylcellulose Barrier Membrane Coated MultiparticulatesADS adapted from 2009 CRS poster,The Influence of Coating System Type on Acetaminophen Release from Ethylcellulose Barrier Membrane Coated Multiparticulates
Surelease® E-7-19020 Product InformationFeatures and benefits of the Surelease E-7-19020, aqueous ethylcellulose coating system.
Surelease® E-7-19030 Product InformationFeatures and benefits of the Surelease E-7-19030, aqueous ethylcellulose coating system.
Surelease® E-7-19040 Product InformationFeatures and benefits of the Surelease E-7-19040, aqueous ethylcellulose coating system.
Surelease® E-7-19050 Product InformationFeatures and benefits of the Surelease E-7-19050, aqueous ethylcellulose coating system.
The Influence of Post Coating Thermal Treatment on Film Properties and Drug Release from Ethylcellulose Barrier Membrane Coating SystemsThe results of this study demonstrate that post coating treatment can affect both physico-mechanical properties of EC films and drug release from EC-coated multi-particulates.
Sureteric® YAE-6-18107 Product InformationFeatures and benefits of Sureteric YAE-6-18107 PVAP (Phthalavin®) based delayed release coating systems.
StarCap 1500® Information Sheet
Starch 1500® Brochure
Technical Evaluation of SureSpheres™ 20/25 Mesh (850-710 micron) as Drug Layering Substrates (Starter Seeds)SureSpheres Application Data - Technical Evaluation - 20/25 Mesh
The Influence of Plasticizer Type and Level on Drug Release from Ethylcellulose Barrier Membrane MultiparticulatesADS adapted from 2009 CRS poster, The Influence of Plasticizer Type and Level on Drug Release from Ethylcellulose Barrier Membrane Multiparticulates
SureSpheres 16/18Product Information
SureSpheres 16/20Product Information
SureSpheres 18/20Product Information
SureSpheres 20/25Product Information
SureSpheres 25/30Product Information
SureSpheres 30/35Product Information
SureSpheres 14/18Product Information
SureSpheres Product Information BrochureSureSpheres features & benefits
Investigation of Ethylcellulose in the Preparation of Theophylline Extended Release Inert Matrix TabletsThis research illustrates the influence of EC particle size and molecular weight on drug release from inert matrices containing a sparingly water soluble drug. The influence of varying the polymer concentration, filler choice and compression force on drug release was also evaluated.
Investigation of Moisture-Activated Granulation of Hydrophilic Polymer Blends in Verapamil HCl Extended Release MatricesADS adapted from 2009 CRS poster, Investigation of Moisture-Activated Granulation of Hydrophilic Polymer Blends in Verapamil HCl Extended Release Matrices
An Introduction to METHOCEL™ Cellulose EthersA description of the METHOCEL line of premium cellulose ethers.
The Influence of Hydrodynamic Conditions on Verapamil Hydrochloride Release from Hydrophilic Matrices Using Ionic and Non-Ionic PolyersThe purpose of this study was to investigate the effects of hydrodynamic conditions on drug release rates from a matrix tablet with a soluble active ingredient, using different combinations of HPMC. The study will show that the combination of HPMC with ionic polymers in ER matrices provides robust formulations which are insensitive to hydrodynamic conditions.
The Influence of In-vitro Dissolution Method on the Release of a Highly Water Soluble Drug from Polyethylene Oxide and Hypromellose Hydrophilic Extended Release MatricesThe objective of this study was to investigate the influence of different dissolution methods on the release of a high solubility drug from an ER matrix formulation containing either HPMC or PEO as the rate-controlling polymer.
