DiBasic Calcium Phosphate replacement with Starch 1500® in a Direct Compression Formula
Data showing the benefits of using Starch 1500 in a direct compression placebo formulation replacing DiCal.

Direct Compression Formula using Starch 1500® with Ranitidine HCL (150mg) Tablets, Film Coated with Opadry® II (85 Series)
Data demonstrating the ability of a formulator challenged with a moisture sensitive active to produce a robust dosage with excellent physical and chemical stability utilizing Starch 1500 in the core and Opadry II as the film coat.

Lactose Replacement with Starch 1500® in a direct compression formula
Data showing that Starch 1500 produces a more robust, more stable placebo tablet via direct compression as compared to a similar lactose based formulation.

The Effect of Starch 1500® on the Stability of Aspirin Tablets Stored Under Accelerated Conditions
Presents data to suggest that Starch 1500 may be inhibiting water activity within the formulation and retarding moisture interaction with the aspirin.

Development of Common Formulations for Both Encapsulation and Tableting - Narrowing the Gap Between Clinical and Commercial Formulations
The successful outcome of this study demonstrates the feasibility of developing a single formula that can be encapsulated into hard gelatin capsules for clinical studies and compressed into tablets for commercialization.

Evaluation of a Partially Pregelatinized Starch in Comparison with Superdisintegrants in a DC Hydrochlorothiazide Formulation
The goal of this study was to compare the tablet disintegration and drug dissolution effectiveness of a partially pregelatinized starch (Starch 1500®) in comparison with various superdisintegrants in a poorly soluble, hydrochlorothiazide direct compaction application.

Modulating Dissolution Profiles of Immediate Release Tablets Using METHOCEL™ E5 LV and a Direct Compression Process
This study investigates the ability of a single METHOCEL™ premium cellulose ether, E5 LV grade to modulate the dissolution profiles of immediate release tablets prepared by direct compression. The research will show that the dissolution rate of all tablets decreases with increasing concentration of METHOCEL™ E5 LV.

Optimizing Lubricant Usage in a Direct Compression Hyrochlorothiazide formulation containing a plastically deforming excipient
This study investigates the use of stearic acid as an alternative to magnesium stearate in the production of pharmaceutical tablets. Also provides guidance on selecting the optimum lubricant level and for a direct compression formulation.

Use of Starch 1500® to Improve the Uniformity of a Low Dose Direct Compression Chlorpheniramine Formulation
This study examines the effect of Starch 1500 as an agent for pre-blending a low dose active to ensure good uniformity in a direct compression chlorpheniramine maleate (4mg) formulation.

The Effect of Core Design and Formulation on the Quality of Film Coated Tablets
This article examines the importance of core design and formulation on the quality of a film coated tablet.