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Capsule Filling Applications

Colorcon® provides superior multifunctional starch based excipients for solid dosage development. Manufactured exclusively for the global pharmaceutical market and backed by industry leading technical expertise, Starch 1500® partially pregelatinized maize starch and StarCap 1500® co-processed starch excipient exhibit properties that make them excellent choices for use as a capsule filler.

 

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Starch 1500, as a flow aid, improves uniformity of capsule fill. As a binder, Starch 1500 facilitates plug formation in equipment and reduces powder fallout when the plug is transferred. The inherent lubricity of Starch 1500 means a lower force to eject material into the capsule shell (compared to other excipients) and leads to reduced wear on equipment.

StarCap 1500 is a unique co-processed mixture of globally accepted excipients designed for use in capsules and tablets. StarCap 1500 is an inert free flowing, low dust excipient with disintegration and dissolution properties that are independent of media pH. StarCap 1500 provides multi-functional benefits through less complex formulations, low capsule and tablet weight variation and ultimately lower overall costs.

Multifunctional Properties

Powders for use as capsule fillers must be free flowing, non-adhesive and cohesive enough to form plugs at low compressive forces. (1) The flow properties of Starch 1500 and StarCap 1500 make them ideal for capsule filling applications. These multifunctional starch excipients provide excellent uniformity of weight and drug content which ultimately results in fewer capsules being rejected on the filling line. The use of these products also corresponds to a cleaner filling operation on high speed production scale equipment.

Contact Colorcon to find out all the ways you can put multifunctional starch excipients to work for you.

 


(1) Dekker, Marcel (2002) Encyclopedia of Pharmaceutical Technology.